Project
Neurotoxicity of agrochemicals in development
Description
For several years, we have focused on studying how exposure to agrochemicals, including glyphosate and its formulations, affects the development, maturation, and function of the nervous system in developing mammals. The presence of these herbicides, as well as their metabolites, has been detected in lakes, rivers, and groundwater, which could suggest that we are dealing with “pseudo-persistent” environmental contaminants. Extensive scientific evidence indicates that exposure to these herbicides induces adverse effects in different animal species. Specifically, in mammals, toxicity has been demonstrated at the cellular, endocrine, reproductive, and nervous system levels following chronic exposure to sublethal doses. We propose to evaluate the neurotoxic effects caused by exposure to these pesticides and to identify the cellular mechanisms underlying these effects in cultured, purified neurons.
Related
Director : Silvana Rosso
Members : Emiliano Gomez Quintero; Conrado Borgatello; Sebastián Luna and Mariano Bisbal.
Spaces/Institutions/Academic Units
Faculty of Biochemical and Pharmaceutical Sciences (UNR), Mercedes and Martín Ferreyra Institute-CONICET (UNC).
Contact
Mail: sbrosso@gmail.com – srosso@fbioyf.unr.edu.ar