Project
Neurotoxicity of agrochemicals in development
Description
For a few years now, we have focused on studying how exposure to agrochemicals, including glyphosate and its formulations, affect the development, maturation and functioning of the nervous system of developing mammals. The presence of these herbicides, as well as their metabolites, has been detected in lakes, rivers, and groundwater, which could suggest that we are facing “pseudo-persistent” contaminants in the environment. There is ample scientific evidence that indicates that exposure to these herbicides would induce adverse effects in different animal species. Specifically, toxicity has been demonstrated in mammals at the cellular, endocrine, reproductive and nervous system levels after chronic exposures to sub-lethal doses. We propose to evaluate the neurotoxic effects caused by exposure to these phytosanitary products as well as to identify the cellular mechanisms that underlie these effects in purified neurons in culture.
Related
Director: Silvana Rosso
Related: Emiliano Gomez Quintero; Conrado Borgatello; Sebastian Luna and MArian Bisbal.
Spaces/Institutions/Academic Units
Faculty of Biochemical and Pharmaceutical Sciences (UNR), Mercedes and Martín Ferreyra-CONICET Institute (UNC).
Contact
Mail: sbrosso@gmail.com – srosso@fbioyf.unr.edu.ar